Bharat Biotech, a city-based vaccine
manufacturer, today announced the launch of Typbar-TCV, the world's
first clinically proven typhoid conjugate vaccine for six months old
infants and adults. Bharat Biotech CMD Krishna M Ella said the new
vaccine brings hope to millions by protecting them against typhoid
caused by salmonella typhi, a highly virulent and invasive enteric
bacterium. Ella said that this is a fourth generation vaccine against
typhoid disease which has been proven to provide long term protection to
adults and infants. Typhoid vaccines fall short in two major counts,
namely long-term protection and protection of children below two years
of age. "We hope this vaccine will reach millions of people and help
reduce the burden of this devastating disease in infants and children,"
Ella told reporters at a press conference here, adding that his company
had commenced commercial production of Typbar-TCV in pre-filled syringes
at its vaccine production facility in Genome Valley. "The pricing of
the vaccine has not yet been decided. There will be two price
structures. One for public institutions and the other one will be for
private organisations. Pricing will be fixed by next week," he said.
The plant has the capacity to produce 10 million doses each year, which
is expandable to 50 million doses per year in future. Bharat Biotech is
the largest producer and supplier of typhoid vaccine in the world,
having distributed over 50 million doses globally, he claimed. Quoting
World Health Organisation reports, Director-General of the International
Vaccine Institute (IVI) Christian Loucq said that typhoid fever kills
between 250,000 to 600,000, besides causing 20 million illnesses per
year, affecting mostly school children. "The World Health Organisation
reports that 90 per cent of typhoid deaths occur in Asia and persists
mainly in children under five years of age. In India, typhoid fever is
observed throughout the year and a greater number of cases coincide with
the rainy season," Loucq said. While typhoid fever can be cured by
antibiotics, resistance to anti-microbials is widespread along with poor
diagnostics, he said, adding that hence prevention of typhoid fever is
better than curing it.
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